Fine-tuning is the production capability most teams underestimate. With a few thousand high-quality examples and a single GPU, a 7 to 14B open-weights model can match or exceed a frontier model on the target task at one to two orders of magnitude lower cost. This guide compares full fine-tuning, LoRA, QLoRA, and DoRA — when each is the right choice, the hardware and dataset requirements, the hyperparameters that matter, the evaluation discipline, and the deployment patterns (merged weights, multi-LoRA serving, hot-swap adapters) that turn one base model into many specialised production endpoints.